Munnerlyn was injured last week against the Texans and had to leave the game.
R.J Stanford will be the team's nickel back.
Munnerlyn had started all 14 games for the Panthers.
The Panthers signed cornerback Jonathan Nelson from the practice squad to take his place.
The Panthers are also likely to be without starting strong safety Charles Godfrey, who is out with a strained right shoulder. He's listed as doubtful after missing practice again on Friday. If Godfrey can't start, then Jordan Pugh will get the nod.
Copyright 2011 by The Associated Press