It wasn't immediately clear where Bush died. Public records show he lived in San Diego, and he had been a pregame commentator for the Chargers' radio broadcast team.
Bush was the Chargers' fourth-round pick out of Washington State in the 1993 draft.
Bush is the seventh player from the Chargers' Super Bowl team who has died, according to The San Diego Union-Tribune. The others are: linebacker David Griggs (1995; car crash), running back Rodney Culver (1996; plane crash), linebacker Doug Miller (1998; struck by lightning), Curtis Whitley (2008; drug overdose), defensive lineman Chris Mims (2008; enlarged heart) and defensive lineman Shawn Lee (Feb. 26; cardiac arrest).
The Associated Press contributed to this report.