Kolb, who was listed as questionable Friday, injured his foot during a Week 8 game against the Baltimore Ravens and has endured a slow, painful recovery.
Cardinals tight end Rob Housler (groin) was inactive, and linebacker Joey Porter (knee) previously had been ruled out. Cornerback Michael Adams, offensive tackle Brandon Keith and tight end Todd Heap was active after being listed as questionable.
Wide receiver Danario Alexander (hamstring) was out for the fifth consecutive game, and running back Cadillac Williams (calf) missed his second consecutive game.
Visit www.nfl.com/inactives to see inactive players in every Sunday game.
The Associated Press contributed to this report.