Mayo returned to practice Friday for the first time since sustaining the injury, but a single practice was not enough to propel him back into action.
Running backs BenJarvus Green-Ellis (toe) and Danny Woodhead (ankle), tight end Aaron Hernandez (knee) and defensive tackle Albert Haynesworth (back) are all active. Cornerback Leigh Bodden (thumb) is out for the Patriots.
Cowboys guard Kyle Kosier will play despite a foot injury.
Visit www.nfl.com/inactives to see inactive players in every Sunday game.