Leading receiver Hakeem Nicks sustained a knee injury during the game and was being evaluated Monday.
Coughlin wasn't sure about either the extent of the injury or which knee was hurt, but the coach said the knee was swollen one day after postgame X-rays were normal.
Nicks also had X-rays on his wrist after Sunday's game, according to the New York Daily News. Tests on the wrist came back negative, the newspaper reported Tuesday.
Coughlin wouldn't speculate if Nicks would be available for Monday night's home opener against the St. Louis Rams.
"I don't know the answer that," Coughlin said. "They're checking all that out."
The Associated Press contributed to this report.