Smith has been recovering from a broken left foot. He has practiced some this week, but on Monday coach Jim Schwartz said he wasn't "game ready" yet. That hasn't changed.
Detroit also listed defensive tackle Nick Fairley and offensive lineman Jason Fox as out with foot injuries. Defensive tackle Andre Fluellen and running back Maurice Morris are probable as they recover from right hand injuries.
Smith started 10 games for the Lions last season and had five interceptions.
Copyright 2011 by The Associated Press