San Francisco 49ers wide receiver Isaac Bruce, who has dealt with a bad ankle for most of the season, rolled it during practice and is questionable to play in Thursday night's game against the Chicago Bears.
"He was doing fine," Singletary said of Bruce. "He was trying to work his way through it. Yesterday, he rolled it."
Bruce, a 16-year NFL veteran, has caught 20 passes for 244 yards this season. He has 1,023 receptions and 91 touchdowns in his career.
Hill also has been bothered by an ankle problem.
The Associated Press contributed to this report.