The trio sat out practice for a second consecutive day and are question marks for Sunday's game against the Chicago Bears.
Hasselbeck has a cracked rib, Tatupu an injured hamstring and Griffith a sprained knee ligament. Seahawks coach Jim Mora says Griffith is most likely to play.
Cornerback Ken Lucas (groin) and defensive tackle Brandon Mebane (calf) were both limited in practice, and wide receivers Deion Branch and T.J. Houshmandzadeh and offensive linemen Chris Spencer and Walter Jones were full participants Thursday.
Copyright 2009 by The Associated Press