Jacobs was hurt after a 5-yard run in the third quarter and walked off the field without a limp after getting medical attention. He also injured his left knee against Baltimore on Nov. 9 and missed the following week's game in Arizona.
"Brandon, it hopefully is not going to be anything big," coach Tom Coughlin said of his star running back.
Philadelphia wide receiver Kevin Curtis left the game with a concussion in the second quarter. Curtis was sidelined earlier in the season after undergoing surgery on a sports hernia during the preseason.
Copyright 2008 by The Associated Press