Published: Oct. 12, 2016 at 10:18 a.m.
Updated: Oct. 16, 2016 at 09:20 a.m.

Start 'Em, Sit 'Em Week 6: Running backs

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Start 'Em & Sit 'Em is the ultimate look at the weekly NFL matchups and how they'll affect your fantasy football team. All starts and sits are based on standard scoring leagues. Obvious fantasy starters like Cam Newton and Antonio Brown will not be featured. For your final lineup decisions, check our lineup rankings.

Byes: Buccaneers, Vikings

Start 'Em

vs.
Start of the Week - Lamar Miller vs. Indianapolis Colts

Miller hasn't scored much so far this season, but he's still fourth in running back touches (116) and should continue to see a lot of work against the Colts. Their defense has surrendered seven total touchdowns and the third-most points to opposing running backs (24.5 PPG), so look for Miller to have his breakout performance.

vs.
C.J. Anderson vs. San Diego Chargers

Anderson's offensive line hasn't done him many favors over the last few weeks, but it's still tough to overlook a tremendous matchup against San Diego on Thursday night. The Chargers have given up 25.4 fantasy points per game to running backs, which ranks second in the league behind New Orleans. Look for Anderson to rebound.

vs.
Jordan Howard vs. Jacksonville Jaguars

My (fantasy) love affair with Howard continued last week, as he rolled the Colts for 163 yards and one touchdown (another touchdown was called back, too). I'd ride him into this week's matchup versus the Jaguars, who have given up 18 fantasy points to Melvin Gordon and 15.5 points to Frank Gore in two of their last three games.

vs.
Christine Michael vs. Atlanta Falcons

The Awakening should continue for Michael, who scored a combined 38.1 fantasy points in his two games before Seattle's bye week and is now set to face the Falcons. Their defense has been vulnerable to running backs, surrendering an average of more than 20 fantasy points per game to the position. Start Michael with confidence.

vs.
Ryan Mathews vs. Washington Redskins

Mathews has been a touchdown-dependant fantasy runner this season, as his yardage totals have been less than impressive in the ground attack. Fortunately for owners, the veteran faces a Redskins defense that has allowed the second-most rushing scores (seven) to running backs this season. Consider Mathews a viable flex option.

Sleepers:
Terrance West at Giants, DeAndre Washington vs. Chiefs

Sit 'Em

vs.
Sit of the Week - Isaiah Crowell vs. Tennessee Titans

Crowell struggled to produce for fantasy fans last week, scoring four fantasy points in what was a blowout loss to the Patriots. Next up is a date with the Titans, who have given up two total touchdowns and the fourth-fewest fantasy points to opposing running backs. Consider Crowell a low-floor No. 2 running back in this matchup.

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T.J. Yeldon vs. Chicago Bears

Yeldon has been difficult to trust, scoring fewer than four fantasy points in two of his last three games. He also averaged 13.7 touches in those contests, and the presence of Chris Ivory in goal-line sets limits his potential. Chicago has held Frank Gore and Theo Riddick to a combined 13.7 fantasy points in their last two games, too.

vs.
Spencer Ware vs. Oakland Raiders

Ware was a hot name in fantasy land to open the season, but his numbers have been less than stellar over his last three games. With Jamaal Charles now at "110 percent," I'd be shocked if Ware sees 10-12 carries this week against the Raiders. Charles appears to be back in the saddle, making Ware a very risky start moving forward.

vs.
Jeremy Hill vs. New England Patriots

Hill has struggled in the last two weeks, scoring a combined 8.3 fantasy points with no touchdowns. He's also dealing with an injured chest and shoulder, which limited him to just 13 snaps in a loss to the Cowboys. Even if Hill is able to suit up in Week 6, the Patriots have surrendered the third-fewest fantasy points (14.2 PPG) to runners.

vs.
Matt Jones vs. Philadelphia Eagles

Jones, a sit 'em in last week's edition, scored 3.6 fantasy points in a win over the Ravens. He's been difficult to trust when the matchup isn't favorable, and that's the case this week when the Redskins host the Eagles. Their defense has been tough on runners, allowing the second-fewest rushing yards (217) in the entire league.

Busts:
Matt Forte vs. Cardinals (MNF), Arian Foster vs. Steelers

Michael Fabiano is an award-winning fantasy football analyst on NFL.com and NFL Network and a member of the Fantasy Sports Writers Association (FSWA) Hall of Fame. Have a burning question on anything fantasy related? Tweet it to @Michael_Fabiano or send a question via Facebook!

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